Defunct brain stem cardiovascular regulation underlies cardiovascular collapse associated with methamphetamine intoxication

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Bioenergetics Failure and Oxidative Stress in Brain Stem Mediates Cardiovascular Collapse Associated with Fatal Methamphetamine Intoxication

BACKGROUND Whereas sudden death, most often associated with cardiovascular collapse, occurs in abusers of the psychostimulant methamphetamine (METH), the underlying mechanism is much less understood. The demonstration that successful resuscitation of an arrested heart depends on maintained functionality of the rostral ventrolateral medulla (RVLM), which is responsible for the maintenance of sta...

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ژورنال

عنوان ژورنال: Journal of Biomedical Science

سال: 2012

ISSN: 1423-0127

DOI: 10.1186/1423-0127-19-16